THROMBOCYTE AND HEALTH
You’ve no doubt heard about thrombocyte somewhere in your comings and goings. If it’s not from health professionals, professors, or medical books giving you an informational list on the subject of thrombocyte and health, there are always loads of great sources available from one resource or another.
But you’ve only got two questions in mind: What is thrombocyte and why is it important?
What is thrombocyte?
Thrombocytes play a key role in blood clotting. They are small blood components whose function is to stop bleeding, sticking to the lining of blood vessels. These cells are produced in the bone marrow. In mammals, thrombocytes are anucleated cell fragments called platelets. Nucleated thrombocytes of nonmammalian vertebrates differ from the mammalian thrombocytes not only in having a nucleus and thus resembling B lymphocytes, but also these nucleated thrombocytes do not aggregate in response to ADP, serotonin and adrenaline (they do aggregate with thrombin, of course).
Thrombocytes gather to stop bleeding at the site of interrupted endothelium. They stick to plug the impairment. Here’s a simplified account of the process:
1. Adhesion. In response to vascular injury, thrombocytes (platelets) bind to specific membrane receptors outside the interrupted endothelium.
2. Activation. A change in shape takes place, receptors becomes activated, and chemical messengers are secreted.
3. Aggregation. Thrombocytes (platelets) become connected to each other. This happens through receptor bridges.
Simply put, thrombocytes is more commonly known as platelets, a blood component crucial to normal blood clotting.
Clot formation is the process where blood forms into a clot, which is an important part of haemostasis. Coagulation (thrombogenesis) is the hematologic undertaking by which blood changes into gel, eventually forming a blood clot. Hemostasis is the cessation of blood loss from damaged blood vessel. In response to injury, the blood vessel wall becomes covered with platelet and fibrin-containing blood clot to stop the bleeding and begin repair of the damaged vessel. Disorders in coagulation can either lead to increased risk of bleeding (hemorrhage) or obstructive clotting (thrombosis).
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