10 Reasons for Low Platelet Count During Pregnancy

10 Causes Of Low Platelet Count During Pregnancy

Platelets are formed in the bone marrow where it undergoes a long production and maturation process under the influence of natural body substances.

However, the display of low platelet count in pregnancy is reported to be possible due to alterations brought about by medical conditions. Some of which are discussed herein.

If developed low platelet count while pregnant, it can be associated to one of the following factors at play or probably all of the three:

1. Reduced production.

2. Increased destruction.

3. Sequestration.

A very low level of platelet count can be dangerous especially with evident bleeding. It will certainly be a horrible situation to experience sudden and uncontrolled flow of blood from the nose, gums, or any other openings of the body.

And sadly, it could happen with a really low platelet count. Before that happens, early management must be performed immediately to prevent the progression in the drop of levels.

It may usually be a costly endeavor but there are affordable options such as all-natural remedies you can learn from money back guaranteed materials like Conquer Low Platelets.


Low platelet count during pregnancy

The common reasons that may lead to low blood platelets during pregnancy are as follows:

1. Preeclampsia or eclampsia.

Preeclampsia is a disorder exclusive to pregnant women where the blood pressure rises to abnormal levels. This increases the risks of damage to different organs of the body both for the woman and more significantly, the fetus.

Eclampsia is a severe form of the condition where the increase in blood pressure can result to damage that is apparent and accompanied by seizures.

It is a serious medical condition that warrants urgent management. Both conditions can be detected at an early stage following routine measurement of blood pressure levels into which every pregnant individual should undertake.

2. HELLP syndrome.

An advanced form of preeclampsia and eclampsia syndrome is HELLP syndrome. The elevation of blood pressure causes damage to the liver and increases the amount of liver enzymes in the blood.

A damaged liver means death of its cells that contain the enzymes. These cells, upon death, release the enzymes of the liver into the bloodstream.

It can be associated with low platelets due to the fact that liver function is required in the formation of platelets. The liver and kidneys also produce erythropoietin that stimulates the bone marrow to produce red blood cells. This hormone is found to have ample effects in regulating platelets.

HELLP means hemolysis of red blood cells, elevated liver enzymes and low platelets.

3. Heparin induced thrombocytopenia.

Almost no individual in the world has never suffered from common colds. But when the illness is associated with streptococcus and improperly treated, it can lead to the development of valvular heart diseases. These diseases can make a person become prone to the development of abnormal blood clots in the body.

There are several factors that can cause abnormal blood clotting in a person which can be damaging and life threatening. In order to prevent the blood clots from harming the person, heparin is usually used.

Heparin use is a known and established causative factor associated with the development of thrombocytopenia. The development of low platelet count that results from the use of heparin is a condition referred to as Heparin-induced thrombocytopenia.

Considering that there are significant reasons where use of heparin is needed in pregnant woman, it puts them at risk to develop having low platelet count.

When heparin is introduced into the body, it may cause the development of antibodies against the drug that influences the activation of platelets. It causes platelets to misbehave with adhesion and aggregation processes resulting to increased consumption that eventually leads to low platelet count.

4. Immune Thrombocytopenic Purpura (ITP).

Immune thrombocytopenic purpura is an immune mediated medical disorder of manifesting reduced platelets in the body. It is mediated by immune cells and antibodies of the body that results in destruction of platelets. It can be classified into two types – primary and secondary.

When the exact cause of immune destruction cannot be mediated it is termed as primary or idiopathic thrombocytopenic purpura.

When the cause of the immune destruction is mediated such as SLE or Hepatitis C, it is termed as secondary thrombocytopenic purpura.

5. Systemic Lupus Erythematosus (SLE).

Systemic lupus erythematosus is an autoimmune disease in which the body attacks itself.

Pregnancy is one of the many conditions that can precipitate or aggravate SLE. In autoimmune diseases, antibodies are formed against the natural components of the body causing it to attack various organs, trying to destroy them.

One of commonly targeted organs is the red bone marrow where platelets and other blood cells are born, developed, and matured. A destruction of the bone marrow results to a fall in the number of all types of blood cells released to the bloodstream.

6. Drug induced.

There are many drugs that can alter any of the steps of platelet formation starting from the totipotent stem cell to megakaryocyte production.

Some of these drugs are commonly used in pregnancy such as fluconazole which is an antifungal agent; ibuprofen and naproxen which are painkillers; and paracetamol which is a very common drug used for fever and headaches.

No drug should be taken without prior discussion with a physician, especially in pregnant women for it won’t only affect a single person but two, including the fetus.


HIV is a sexually transmitted illness that started dominance in the beginning of this century. It can be spread through blood and blood products, sexual contact, as well as from the parent to her child (when the child is in the mother’s womb).

HIV indirectly attacks all the systems of the body. It destroys the immune system of a person that comprises the supposedly only primary defense system to protect the body.

A weakened immune system gives opportunity to many type of infections that hover around the body for successful invasion. Some of these infections cause destruction of the bone marrow, which would also mean a destruction of platelets.

When HIV destroys the bone marrow, it can reduce the platelet count directly.

8. Aplastic anemia.

Aplastic anemia is a disease that affects platelet count also because of an impaired red bone marrow. The condition is possible during pregnancy, similarly causing a reduction in platelet count.

Aplastic anemia means complete destruction of the red bone marrow. The cause of damage can be due to a bacteria, virus, drug, autoimmunity, or irradiation.

Depending on the cause of aplastic anemia in the pregnant woman, the treatment will vary.

9. Disseminated Intravascular Coagulation (DIC).

Disseminated intravascular coagulation is a disease that can be encouraged by a number of pregnancy-related medical conditions but it can be the pregnancy itself.

In DIC, there is widespread clotting that causes a consumption of platelets inside the blood vessels. This also results to a low platelet count.

Some conditions that can give rise to DIC during pregnancy is the presence of infection as well as autoimmune disorders.

10. Cancer.

There are different kinds of cancer that can affect a person depending on carried predisposing risk factors. Pregnancy can be one of the risk factors for certain types.

Myelodysplastic syndromes and lympoproliferative syndromes are common types of cancer that can affect pregnant women where low platelet count can be observed.

These medical conditions destroy the bone marrow and take up the space normally used for platelet formation and replacing it with cancer cell growth. They can also cause disseminated intravascular coagulation.


Low Platelet Count in Pregnancy is NOT Very Common

This is not a full exclusive list to detail causes of low platelet count in pregnancy but covers some of the common ones. Read essentials about normal platelet count in pregnancy.

Low platelet count in pregnancy is not a very common condition but can be present in a significant number of patients. The condition can be detected at an early stage with routine blood tests and follow up during the course of pregnancy. Therefore, regular check-up is essential.

The importance of regular follow-up cannot be emphasized enough.


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